Microtubule Assembly: Catastrophe Factors to the Rescue
نویسندگان
چکیده
Two new studies have shown how regulation of microtubule dynamics by members of the kinesin superfamily may guard against errors in spindle assembly and chromosome segregation.
منابع مشابه
The mechanisms of microtubule catastrophe and rescue: implications from analysis of a dimer-scale computational model
Microtubule (MT) dynamic instability is fundamental to many cell functions, but its mechanism remains poorly understood, in part because it is difficult to gain information about the dimer-scale events at the MT tip. To address this issue, we used a dimer-scale computational model of MT assembly that is consistent with tubulin structure and biochemistry, displays dynamic instability, and covers...
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عنوان ژورنال:
- Current Biology
دوره 13 شماره
صفحات -
تاریخ انتشار 2003